Response to commentaries: Neither optimism or nihilism… but reasons for hope

Scleroderma: From Therapeutic Nihilism to Therapeutic Optimism

Several types of inflammatory cells infiltrate the affected tissue. Different subsets of “T” lymphocyte may be observed in different affected organs in various stages of SSc. CD4 lymphocytes are increased in the affected skin, whereas CD8 lymphocytes are found more commonly in bronchoalveolar lavage of patients who have scleroderma-related interstitial lung disease (ILD). Several autoantibodies...

Eating or Feeding Our Young: A Response to Recent Commentaries

Reasons for Cautious Optimism

Luis G. Melo, Alok S. Pachori, Deling Kong, Massimiliano Gnecchi, Kai Wang, Richard E. Myocardium : Reasons for Cautious Optimism Molecular and Cell-Based Therapies for Protection, Rescue, and Repair of Ischemic Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2004 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Aven...

Hope, optimism and delusion

Optimism is generally accepted by psychiatrists, psychologists and other caring professionals as a feature of mental health. Interventions typically rely on cognitive-behavioural tools to encourage individuals to 'stop negative thought cycles' and to 'challenge unhelpful thoughts'. However, evidence suggests that most individuals have persistent biases of optimism and that excessive optimism is...

Pancreatic cancer and cancer screening programs: from nihilism to hope.